Freeze-etching studies on ultrastructural changes of endothelial cells in the thyroid of normal,TSH-treated and Thyradin-treated mice |
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| Authors: | Kazunori Ishimura Hisao Okamoto Dr Hisao Fujita |
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| Institution: | (1) Department of Anatomy, Hiroshima University School of Medicine, Hiroshima, Japan;(2) Department of Anatomy, Hiroshima University School of Medicine, Kasumi 1-2-3, 734 Hiroshima, Japan |
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| Abstract: | Summary Freeze-etching images of the capillary endothelium in the thyroid of normal, TSH-treated and Thyradin (powdered thyroid)-treated mice were examined. Numerous pores represent vesicular stomata or fenestrations. The number of the pores and their population density are increased in TSH-treated mice, and decreased in Thyradin-treated animals. In addition, the width of the parajunctional zone and of the flat ray free from endothelial pores is smaller in TSH-treated mice and larger in Thyradin-treated animals. These facts indicate that the number of endothelial pores changes according to the functional activity of the gland.Supported by a grant from the Japanese Educational Ministry |
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| Keywords: | Thyroid gland Endothelial pores TSH-treatment Thyradin treatment Freeze-etching |
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