Simple ortho- and para-hydroquinones as compounds neuroprotective against oxidative stress in a manner associated with specific transcriptional activation |
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| Authors: | Takumi Satoh Sachie Saitoh Kunio Kosaka |
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| Affiliation: | a Department of Welfare Engineering, Faculty of Engineering, Iwate University, Ueda 4-3-5, Morioka, Iwate 020-8551, Japan
b Research and Development Center, Nagase Co., Ltd., Kobe, Hyogo 651-2241, Japan |
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| Abstract: | |
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| Keywords: | ARE, antioxidant-responsive element BSA, bovine serum albumin CA, carnosic acid DEM, diethylmalate FA, fumaric acid Dt-BHQ, 2,5-di-tert-butylhydroquinone GSH, reduced glutathione MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide NEM, N-ethylmaleimide NEPP, neurite outgrowth-promoting prostaglandin PBS, Ca2+, Mg2+ (&minus )-phosphate-buffered saline PED, pro-electrophilic drug S-DOSA, simple detection of oxidative stress by serum albumin TBHQ, tert-butyl hydroquinone. |
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