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In vitro activation of GAT1 transporters expressed in spinal cord gliosomes stimulates glutamate release that is abnormally elevated in the SOD1/G93A(+) mouse model of amyotrophic lateral sclerosis
Authors:Marco Milanese  Simona Zappettini  Emanuela Jacchetti  Tiziana Bonifacino  Chiara Cervetto  Cesare Usai  Giambattista Bonanno
Institution:1. Department of Experimental Medicine, Section of Pharmacology and Toxicology and Center of Excellence for Biomedical Research, University of Genova, Genova, Italy;2. These two authors equally contributed to this paper.;3. Institute of Biophysics, National Research Council, Genova, Italy;4. National Institute of Neuroscience, Torino, Italy
Abstract:
Keywords:amyotrophic lateral sclerosis  astrocytes  GABA transporters  glutamate release
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