Of rabbit and man: Comparative gene mapping |
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| Authors: | Joëlle Soulie J de Grouchy |
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| Institution: | (1) E.R. 149 C.N.R.S., Hôpital Necker-Enfants-Malades, 149, rue de Sèvres, F-75743 París Cedex 15, France;(2) U. 173 I.N.S.E.R.M., Hôpital Necker-Enfants-Malades, 149, rue de Sèvres, F-75743 París Cedex 15, France |
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| Abstract: | Summary Nineteen cell hybrids were obtained by fusing rabbit (Oryctolagus cuniculus, OCU) fibroblasts and a Chinese hamster cell line HGPRT. Eleven enzymatic markers were investigated for cosegregation analysis. Seven could be assigned to OCU chromosomes: LDHA to OCU1; LDHB and TPI to OCU4; PEPB, NP, and ITP to OCU16; and G6PD to OCUX. Two assignments were considered possible: MDH2 to OCU15, and GUK to OCU3 or 15. Two could not be assigned: MDH1 and PGD. These results are consistent with the OCU-HSA chromosome homocologies previously reported, except for PEPB. |
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