A periodic ultrastructure in intermediate filaments |
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| Authors: | D Henderson N Geisler K Weber |
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| Affiliation: | Max-Planck-Institute for Biophysical Chemistry D-3400 Göttingen Federal Republic of Germany |
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| Abstract: | Intermediate sized filaments reconstituted in vitro from purified desmin, epidermal keratin and the Mr 68,000 protein of neurofilaments were examined after high resolution metal shadowing. The filaments demonstrate a marked longitudinal periodicity of about 21 nm. This is the first procedure that allows detection of a periodic substructure in these filaments using the electron microscope. |
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