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Selective antisense oligonucleotide inhibition of human IRF4 prevents malignant myeloma regeneration via cell cycle disruption |
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| Authors: | Phoebe K Mondala Ashni A Vora Tianyuan Zhou Elisa Lazzari Luisa Ladel Xiaolin Luo Youngsoo Kim Caitlin Costello A Robert MacLeod Catriona HM Jamieson Leslie A Crews |
| Institution: | 1. Division of Regenerative Medicine, Department of Medicine, University of California, San Diego, La Jolla, CA 92093, USA;2. Ionis Pharmaceuticals, Carlsbad, CA 92008, USA;3. Moores Cancer Center at University of California, San Diego, La Jolla, CA 92093, USA;4. Division of Blood and Marrow Transplantation, Department of Medicine, University of California, San Diego, La Jolla, CA 92093, USA |
| Abstract: |  |
| Keywords: | multiple myeloma cancer stem cells IRF4 interferon regulatory factor 4 MYC CXCR4 cell cycle antisense oligonucleotide bone marrow translational research |
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