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Poly(8-bromo-2'-deoxyadenylic acid): the syn/anti relationship |
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| Authors: | V Amarnath T L Miller A D Broom |
| Abstract: | The synthesis of a high-molecular-weight, putatively all-syn DNA analogue, poly(8-bromo-2'-deoxyadenylic acid), is described. The syn----anti transition was shown to be both salt and temperature dependent. Conditions were found which favored 'normal' Watson-Crick pairing and duplex formation with poly(dT). |
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