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Seropositivity is associated with insulin resistance in patients with early inflammatory polyarthritis: results from the Norfolk Arthritis Register (NOAR): an observational study |
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| Authors: | Hoda Mirjafari Tracey M Farragher Suzanne MM Verstappen Allen Yates Diane Bunn Tarnya Marshall Mark Lunt Deborah PM Symmons Ian N Bruce |
| Institution: | (1) Arthritis Research UK Epidemiology Unit, University of Manchester, Manchester Academic Health Sciences Centre, Oxford Road, Manchester, M13 9PT, UK;(2) Department of Biostatistics, University of Liverpool, Brownlow Street, Liverpool, L69 3GS, UK;(3) Clinical Research Department, Manchester Royal Infirmary, Oxford Road, Manchester, M13 9WL, UK;(4) Norfolk Arthritis Register, Norfolk and Norwich University Hospital, Colney Lane, Norwich, NR2 3SR, UK |
| Abstract: | IntroductionCardiovascular disease (CVD) is the leading cause of death in patients with inflammatory polyarthritis (IP), especially in seropositive disease. In established rheumatoid arthritis (RA), insulin resistance (IR) is increased and associated with CVD. We investigated factors associated with IR in an inception cohort of patients with early IP. |
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