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Reduced expression of perchloric acid-soluble protein after partial hepatectomy in rats
Authors:Kanouchi Hiroaki  Taga Masaki  Okamoto Takeaki  Yamasaki Masao  Oka Tatsuzo  Yamada Koji  Tone Shigenobu  Minatogawa Yohsuke
Affiliation:Department of Biochemistry, Kawasaki Medical School, Okayama, Japan. kanouchihiroaki@mac.com
Abstract:
We examined the expression of perchloric acid-soluble protein (PSP) during liver regeneration after partial hepatectomy (PH) in rats. Liver regeneration was almost complete at 7-d after PH. Expression of PSP protein and mRNA decreased and then gradually increased during liver regeneration. An immunohistochemical study showed that PSP is distributed in cytosol and nuclei in normal liver, but localization in the nuclei was not be recognized in the regenerated liver.
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