Reduced expression of perchloric acid-soluble protein after partial hepatectomy in rats |
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Authors: | Kanouchi Hiroaki Taga Masaki Okamoto Takeaki Yamasaki Masao Oka Tatsuzo Yamada Koji Tone Shigenobu Minatogawa Yohsuke |
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Affiliation: | Department of Biochemistry, Kawasaki Medical School, Okayama, Japan. kanouchihiroaki@mac.com |
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Abstract: | We examined the expression of perchloric acid-soluble protein (PSP) during liver regeneration after partial hepatectomy (PH) in rats. Liver regeneration was almost complete at 7-d after PH. Expression of PSP protein and mRNA decreased and then gradually increased during liver regeneration. An immunohistochemical study showed that PSP is distributed in cytosol and nuclei in normal liver, but localization in the nuclei was not be recognized in the regenerated liver. |
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