| 肺炎链球菌疫苗研制进展 |
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| 引用本文： | 朱学喆,赵志强,谢贵林.肺炎链球菌疫苗研制进展[J].微生物学免疫学进展,2013(1):58-64. |
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| 作者姓名： | 朱学喆 赵志强 谢贵林 |
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| 作者单位： | 兰州生物制品研究所有限责任公司甘肃省疫苗工程技术研究中心 |
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| 基金项目： | 国家“863”计划疫苗研发关键技术及产品研发项目课题支持2012AA02A401 |
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| 摘 要： | 肺炎链球菌导致的疾病已成为全球一个重要的公共卫生问题。疫苗开发及使用成为重要的预防策略,目前肺炎球菌疫苗主要有多糖疫苗和多糖蛋白结合疫苗二类。对肺炎链球菌病原学、流行病学、所致疾病、疫苗研发进展及疫苗使用情况进行了综述。
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| 关 键 词： | 肺炎球菌 荚膜多糖 蛋白质结合疫苗 |
Research progress on pneumococcal vaccine |
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| ZHU Xue-zhe,ZHAO Zhi-qiang,XIE Gui-lin.Research progress on pneumococcal vaccine[J].Progress In Microbiology and Immunology,2013(1):58-64. |
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| Authors: | ZHU Xue-zhe ZHAO Zhi-qiang XIE Gui-lin |
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| Institution: | (Lanzhou Institute of Biological Products Co.Ltd.,Center for Gansu Provincial Vaccine Engineering Research, Lanzhou 730046,China) |
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| Abstract: | Pneumococcal disease is a major public health problem all over the world.Pneumococcal vaccine development and application become an important prevention strategy nowadays,which includes pneumococcal polysaccharide vaccine and pneumococcal polysaccharide-protein conjugate vaccine.Streptococcus pneumoniae etiology,epidemiology,diseases and pneumococcal vaccine research and application progress are summed up respectively in this review. |
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| Keywords: | Pneumococcus Capsular polysaccharide Protein Conjugate vaccine |
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