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A Murine ESC-like State Facilitates Transgenesis and Homologous Recombination in Human Pluripotent Stem Cells
Authors:Christa Buecker  Hsu-Hsin Chen  Jose Maria Polo  Laurence Daheron  Lei Bu  Tahsin Stefan Barakat  Patricia Okwieka  Andrew Porter  Joost Gribnau  Konrad Hochedlinger  Niels Geijsen
Affiliation:1. Center for Regenerative Medicine, Harvard Medical School, Massachusetts General Hospital, 185 Cambridge Street, Boston, MA 02114, USA;2. Cancer Center, Harvard Medical School, Massachusetts General Hospital, 185 Cambridge Street, Boston, MA 02114, USA;3. Cardiovascular Research Center, Harvard Medical School, Massachusetts General Hospital, 185 Cambridge Street, Boston, MA 02114, USA;4. Harvard Stem Cell Institute, Harvard University, Cambridge, MA 02138, USA;5. Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138, USA;6. Department of Reproduction and Development, Erasmus MC, University Medical Center, 3000 CA Rotterdam, The Netherlands;7. Gene Therapy Group, Department of Haematology, Imperial College London, Hammersmith Hospital Campus, Du Cane Rd, London W12 ONN, UK;8. Hubrecht Institute for Developmental Biology and Stem Cell Research, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands
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