LH inhibitory properties of aqueous extracts of rat pineal glands |
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| Authors: | R J Orts B Benson B F Cook |
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| Institution: | Department of Anatomy The University of Texas Medical Branch Galveston, Texas 77550, USA |
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| Abstract: | Crude aqueous extracts of rat pineal glands markedly inhibited the 24 and 48 hour postcastration rise of serum LH in mature male rats. After partial purification by exclusion chromatography on Sephadex G-25 the LH inhibitory activity was found to reside in a volume not coinciding with that of melatonin, indicating that some substance other than this indole may be responsible for the anti-LH property in aqueous extracts of rat pineal glands. |
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