A method for analyzing censored survival phenotype with gene expression data |
| |
| Authors: | Tongtong Wu Wei Sun Shinsheng Yuan Chun-Houh Chen Ker-Chau Li |
| |
| Institution: | (1) Department of Epidemiology and Biostatistics, University of Maryland, College Park, MD 20742, USA;(2) Department of Biostatistics, Genetics, Carolina Center for Genome Science, University of North Carolina, Chapel Hill, NC 27599, USA;(3) Institute of Statistical Science,Academia Sinica, Taipei, 115, Taiwan;(4) Department of Statistics, University of California, Los Angeles, CA 90095-1554, USA |
| |
| Abstract: | Background Survival time is an important clinical trait for many disease studies. Previous works have shown certain relationship between
patients' gene expression profiles and survival time. However, due to the censoring effects of survival time and the high
dimensionality of gene expression data, effective and unbiased selection of a gene expression signature to predict survival
probabilities requires further study. |
| |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ |
|
