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Breakthrough Hormographiella aspergillata Infection in a Patient with Acute Myeloid Leukemia Receiving Posaconazole Prophylaxis: A Case Report and Review |
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| Authors: | Isabel Cristina Ramírez-Sanchez Diana Agredo Karen Arango |
| Institution: | 1.Infectious Diseases Section, Internal Medicine Department, Hospital Pablo Tobón Uribe, Universidad de Antioquia Medical School, calle 78B#69-240, Medellín, Colombia ;2.Infectious Diseases Section, Internal Medicine Department, Universidad de Antioquia Medical School, Medellín, Colombia ;3.Unidad de Micología Medica y Experimental, Corporación Para Investigaciones Biológicas, Universidad de Antioquia, Universidad Pontificia Bolivariana, Medellín, Colombia ; |
| Abstract: | Breakthrough invasive infections occur in immunosuppressed patients while they are receiving antifungal agents for both prophylaxis and therapy. Under such conditions, unusual fungal infections emerge. Hormographiella aspergillata is considered an uncommon human pathogen and causes devastating infections. Here, we present a case report of necrotizing pneumonia caused by H. aspergillata as a breakthrough infection in a neutropenic patient and review all previous cases of H. aspergillata infection reported in the literature. |
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