Chiral reagents for the determination of enantiomeric excess and absolute configuration using NMR spectroscopy |
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| Authors: | Wenzel Thomas J Wilcox James D |
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| Institution: | Department of Chemistry, Bates College, Lewiston, Maine, USA. Twenzel@bates.edu |
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| Abstract: | Recent advances in the development of chiral derivatizing and solvating agents that facilitate the determination of enantiomeric excess and absolute configuration are reviewed. These include metal-containing species, host-guest systems, donor-acceptor compounds, and liquid crystal discriminating agents. In the aggregate, these reagents can be used to analyze a wide range of compound classes. |
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| Keywords: | NMR chiral shift reagents enantiomeric excess absolute configuration chiral derivatizing agent chiral solvating agent |
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