Tissue reactions under chronic exposure to ionizing radiation |
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| Authors: | A. V. Akleyev |
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| Affiliation: | (1) First Department of Internal Medicine, Sapporo Medical University School of Medicine, S-1, W-16, Chuo-ku, Sapporo 060-8543, Japan;(2) Division of Molecular Oncology and Molecular Diagnosis, Graduate School of Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan;(3) Department of Radiology, Sapporo Medical University School of Medicine, Sapporo, Japan; |
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| Abstract: | Reviewed are radiobiological data on the emergence of tissue reactions that may determine the course and outcome of human chronic irradiation. The main mechanisms of the reaction of hemopoietic, immune, reproductive, endocrine, respiratory systems and skin to long-term and fractionated exposure to ionizing radiation are considered. The problem of developing a new approach to threshold dose estimation for chronic exposure effects is discussed. |
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