Na+,K+-ATPase and Mg2+-ATPase Activities in Different Regions of Rat Brain During Alloxan Diabetes |
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| Authors: | C S K Mayanil S M I Kazmi N Z Baquer |
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| Institution: | Hormone and Drug Research Laboratory, School of Life Sciences, Jawaharlal Nehru University, New Delhi, India |
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| Abstract: | The effect of alloxan diabetes on the activities of Na+,K+-ATPase and Mg2+-ATPase was studied in three regions of rat brain at various time intervals after the onset of diabetes. It was observed that Na+,K+-ATPase activity increased at early time intervals after diabetes, followed by a recovery to near control levels in all three regions of the brain. There was an overall increase in Mg2+-ATPase activity in all the regions. A reversal of the effect was observed with insulin administration to the diabetic rats. |
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| Keywords: | Na+ K+ ATPase-Mg2+ ATPase Dopamine Norepinephrine Diabetes Brain Insulin |
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