The influence of inorganic silicon (Si) on pituitary-thyroid axis |
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Authors: | Jacek Najda Jan Gmiński Marian Dróżdż Franciszek Zych |
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Institution: | (1) Department of Biochemistry and Chemistry, Silesian Medical Academy, ul Medyków 18, 40-752 Katowice, Poland;(2) Department of Patophysiology, Silesian Medical Academy, ul. Medyków 18, 40-752 Katowice, Poland |
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Abstract: | The influence of silicon-treatment on the levels of TSH and thyroid hormones was studied in rats. Concentrations of thyrotropin
(TSH), triiodothyronine (T3), and thyroxine (T4) were estimated in sera of rats receiving per os a soluble silicon compound—sodium metasilicate nonahydrate (Na2SiO3·9H2O), dissolved in the animals' drinking water. An increase in the TSH level in the tested group was observed, without statistically
significant differences in T3 and T4 concentrations between the two groups of animals. The results provide evidence for the influence of silicon on the endocrine
balance. They could also prove that this chemical element is capable of modifying the rate of some hormones' synthesis. |
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Keywords: | Silicon thyroid stimulating hormone (TSH) triiodothyronine (T3) thyroxine (T4) |
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