Effect of marinobufagenin on the primary reinforcing effect of ethanol] |
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| Authors: | V A Kashkin N A Patkina A Ia Bagrov Ia Iu Bagrov E E Zvartau |
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| Affiliation: | St. Petersburg I. P. Pavlov State Medical University, 197022, St. Petersburg, Leo Tolstoy St., 6/8, Russia. |
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| Abstract: | ![]()
Intraperitoneal administration of marinobufagenin resulted in a reliable and dose-dependent suppression of ethanol self-administration in drug- and experimentally naive DBA/2 mice. The findings suggest that Na/K-ATPase contributes to both mediation of the ethanol reinforcing properties and the mood regulation. |
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