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redPATH:Reconstructing the Pseudo Development Time of Cell Lineages in Single-cell RNA-seq Data and Applications in Cancer
Authors:Kaikun Xie  Zehua Liu  Ning Chen  Ting Chen
Affiliation:1. Institute for Artificial Intelligence, State Key Lab of Intelligent Technology and Systems, Department of Computer Science and Technology, Tsinghua University, Beijing 100084, China;2. Tsinghua-Fuzhou Institute of Digital Technology, Beijing National Research Center for Information Science and Technology, Tsinghua University, Beijing 100084, China;3. Center for Computational and Integrative Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA;4. Department of Molecular Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA;5. Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA 02142, USA
Abstract:
Keywords:Single-cell pseudotime reconstruction  Consensus Hamiltonian path  Cell differentiation  Cell proliferation  Cell development and diseases
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