| 辐射对大鼠肺巨噬细胞Fc受体表达和特异吞噬功能的影响 |
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| 引用本文： | 胡连平,龚诒芬,吴德昌.辐射对大鼠肺巨噬细胞Fc受体表达和特异吞噬功能的影响[J].分子细胞生物学报,1989(4). |
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| 作者姓名： | 胡连平 龚诒芬 吴德昌 |
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| 作者单位： | 放射医学研究所 北京
(胡连平，龚诒芬)，放射医学研究所 北京(吴德昌) |
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| 摘 要： | 以往的实验表明,巨噬细胞(Macrophages简称Mф)对一定辐射剂量内的照射表现出较强的辐射抗性。因此学者们转向研究照射后时间依赖性的Mф损伤变化。这主要是涉及照射后所致的迟发损伤效应。有关大剂量照射后,短时间观察Mф损伤效应的研究报道甚少。为此本文观察了大鼠肺巨噬细胞(AlveolarMacrophages简称AM)在体外受100—500 Gy
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| 关 键 词： | 巨噬细胞 吞噬 辐射. |
RADIATION EFFECTS ON EXPRESSION OF FC-RECEPTOR OF ALVEOLAR MACROPHAGES OF RAT AND THEIR SPECIFIC PHAGOCYTOSIS |
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| Hu Lian-ping Gong Yi-fen and Wu De-chang.RADIATION EFFECTS ON EXPRESSION OF FC-RECEPTOR OF ALVEOLAR MACROPHAGES OF RAT AND THEIR SPECIFIC PHAGOCYTOSIS[J].Journal of Molecular Cell Biology,1989(4). |
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| Authors: | Hu Lian-ping Gong Yi-fen and Wu De-chang |
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| Abstract: | BCG-activated alveolar macrophages(AM)of Wistar rats were irradiated with differentdoses of gamma-ray in vitro.The effects ofradiation on the expression of their Fc-recep-tor and specific phagocytic activity wereobserved.AM,after irradiation with doses of0,100,300 and 500 Gy,showed decreasingphagocytic activity to chicken red blood cells(CRBC) opsonized with anti-CRBC antibodywith no change in phagocytic indices.Theexpression of Fc-receptor of AM was,how-ever,increased. |
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| Keywords: | Macrophages Phagocytosis Radiation |
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