Three new taxanes with the 10-alkoxy group from the heartwood of Taxus cuspidata |
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| Authors: | Dong Mei Zhang Man-Li Wang Yu-Fang Zhang Xi-Ping Li Cun-Fang Shi Qing-Wen Cong Bin Kiyota Hiromasa |
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| Institution: | College of Basic Medicinal Sciences, Hebei Medical University, Shijiazhuang, PR China. |
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| Abstract: | Three novel taxanes with the 10-alkoxy group were isolated from heartwood of Taxus cuspidata. The structures were identified as 2alpha,14beta-diacetoxy-10beta-ethoxytaxa-11,4(20)-dien-5alpha-ol (1), 2alpha,14beta-diacetoxy-10beta-methoxytaxa-11,4(20)-dien-5alpha-ol (2), and 2alpha-acetoxy-10beta-ethoxytaxa-11,4(20)-diene-5alpha,14beta-diol (3) on the basis of spectroscopic analysis. These are the first taxanes with an alkoxy moiety on the skeleton. |
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