Assessment of intraparticle biocatalytic distributions as a tool in rational formulation |
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Authors: | van Roon Jeroen Beeftink Rik Schroën Karin Tramper Hans |
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Institution: | Wageningen University, Department of Agrotechnology and Food Sciences, Food and Bioprocess Engineering Group, PO Box 8129, 6700 EV, Wageningen, The Netherlands. jeroen.vanroon@algemeen.pk.wau.nl |
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Abstract: | Research has shown that the intraparticle biocatalytic distribution has extensive effects on the properties of various (industrial) biocatalytic particles and their performance in (bio-) chemical reactions. In recent years, advances in molecular chemistry have led to the development of many different specific (immuno-) labeling and light-microscopic detection techniques. Furthermore, high-quality image-digitizing devices and enhanced computing power have made image analysis readily accessible. These technologies may lead to the assessment and improvement of the internal biocatalyst profile as an integral part of biocatalytic particle optimization. |
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