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Antitrypanosomal activities and cytotoxicity of 5-nitro-2-furancarbohydrazides
Authors:Millet Régis  Maes Louis  Landry Valérie  Sergheraert Christian  Davioud-Charvet Elisabeth
Affiliation:

a UMR 8525 CNRS, Université de Lille 2, Institut de Biologie de Lille et Institut Pasteur de Lille, 1 rue du Professeur Calmette, BP 447, F-59021, Lille, France

b Tibotec, L11 Gen. de Wittelaan, B-32800, Mechelen, Belgium

Abstract:
A series of 5-nitro-2-furancarbohydrazides were synthesized. In vitro antitrypanosomal activities of these compounds were determined against the closely related protozoa Trypanosoma cruzi Trypanosoma brucei and discussed in relation to potential targets.
Keywords:
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