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| 噬菌体抗体库的优化 | |
| 引用本文： | 吴丽金,陈宇光. 噬菌体抗体库的优化[J]. 生物学杂志, 2001, 18(6): 10-12 |
| 作者姓名： | 吴丽金 陈宇光 |
| 作者单位： | 上海大学生命科学学院,上海,200436 |
| 摘 要： | 噬菌体抗体组合文库技术作为噬菌体展示和抗体组合文库两种技术的集成，由于它具有库容量大、特异性高、和敏感性强的优点而被誉为抗体技术的第三次革命。但是由于一些技术上的原因，使得它无法得到广泛的应用，本文就其优化进行综述。 |
| 关 键 词： | 噬菌体展示 抗体库 PCR技术 单链抗体 |
| 文章编号： | 1008-9632(2001)06-0010-03 |
| 修稿时间： | 2001-09-28 |
The improvement of phage display antibody library |
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| WU Li-jin,CHEN Yu-Guang. The improvement of phage display antibody library[J]. Journal of Biology, 2001, 18(6): 10-12 | |
| Authors: | WU Li-jin CHEN Yu-Guang |
| Abstract: | Phage antibody library is the combination of phage display and antibody library.Due to its large content?high specificity and sensitivity,It has been described as the third revolution in antibody technology.But its general application is still limited because of several technical difficulties.This review mainly addresses how to improve it by some methods. |
| Keywords: | phage display antibody libraries PCR technology ScFv. |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |