昆虫化学感受蛋白（CSPs）的功能研究概述

昆虫的嗅觉系统与其各项生命活动息息相关，化学感受蛋白（CSPs）是嗅觉系统中的重要组成部分，可以结合气味或信息素分子，并传递给嗅觉受体，完成嗅觉相关功能。随着分子生物学技术和测序手段的不断发展，越来越多的昆虫CSPs得到鉴定。CSPs在昆虫体内广泛分布于触角、跗节、下颚须等化学感受器官，同时也在表皮、腹部、体躯等非感受器官大量表达，具有感知化学分子的功能并且与昆虫生长、发育、繁殖等生理功能及昆虫对杀虫剂的抗性相关。本文通过从CSPs的发现和命名、分子特性、结构及分布等方面展开综述，着重介绍CSPs的气味分子识别作用机制、抗药性机制及功能分类，以期为今后利用CSPs作为靶标防治害虫提供参考。

Overview of functional research on insect chemosensory proteins (CSPs)

The olfactory system of insects is closely related to its various life activities. Chemosensory proteins (CSPs)are an important part of the olfactory system, which can bind odor or pheromone molecules and transmit them to olfactory receptors and perform olfactory-related functions. With the development of molecular biology and sequencing technology, more and more insect CSPs have been identified. CSPs are widely distributed in chemical sensing organs such as antennae, tarsus and mandibular whiskers in insects. At the same time, they are also expressed in non sensing organs such as epidermis, abdomen and body. They have functions of sensing chemical molecules and are related to the physiological functions of insect growth, development and reproduction and insect resistance to insecticides. In this study, the discovery, naming, molecular properties, structure and distribution of CSPs were reviewed, and the odor molecular recognition mechanism, insecticide resistance mechanism and functional classification of CSPs were introduced. It is expected to provide reference for using CSPs as a target to control pests in the future.