水稻矮缩病毒基因组数据库的构建

二级数据库的构建是生物信息学新的重要领域。目前部分生物的基因组序列测定完成后，正在进行广泛而深入的结构和功能研究，使二级数据库的重要性显得日益突出。水稻矮缩病毒是一种在日本、中国和东南亚感染水稻的病原微生物，给农业生产造成很大损失。根据国际和国内对水稻矮缩病毒基因组的研究，利用已有的基因序列和结构、功能等方面的数据，以计算机网络为载体，参考国际通用数据库的格式，尝试建立一个简洁的、友好的通用性好而且专用性强的二级数据库：水稻矮缩病毒基因组数据库。希望能够为研究普通水稻矮缩病毒的粒子结构、基因表达调控、致病机理和防治方法提供一个良好的工具，为从事水稻矮缩病理论和应用研究的工作者提供方便和帮助，并为探索二级数据库的构建积累经验。

CONSTRUCTION OF RICE DWARF VIRUS GENOME DATABASE

Secondary database construction is an important subject in the field of bioinformatics. As the full genomic sequences of some organisms are being completed and followed by structural and functional studies, construction of secondary database becomes essential on the agenda. The rice dwarf virus (RDV) is a pathogen infecting rice in China, Japan and the Southeastern Asia region and leading to considerable economic loss. Based on the data generated from recent genomic research and earlier biochemical studies scattered in various primary databases and scientific journals, we have constructed a compact, user-friendly and non-redundant job-oriented secondary database. This work will provide compiled useful information for plant molecular biologists as well as in achieving preliminary experiences in secondary database construction.