Cyclic fluctuations of the mitotic Ca2+-ATPase during the cell cycle of the myxomycete Physarum polycephalum |
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| Authors: | C Petzelt D Auel W Sachsenmaier |
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| Affiliation: | 1. Department of Chemistry–Ångström, Uppsala University, Box 573, 75123 Uppsala, Sweden;2. Department of Medicinal Chemistry, Uppsala University, Box 574, 75123 Uppsala, Sweden;1. School of Health and Life Sciences, Aston University, Aston Triangle, Birmingham B4 7ET, UK;2. School of Physics and Astronomy and The Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, UK;3. Department of Biology, University of York, York YO10 5DD, UK;4. Manchester Institute of Biotechnology, University of Manchester, Manchester M1 7DN, UK;5. Biocleave, 154AH Brook Drive, Milton Park, Abingdon, Oxfordshire OX14 4SD, UK |
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| Abstract: | The occurrence of the mitotic Ca2+-ATPase, resembling the enzyme described for higher organisms, is demonstrated in multinuclear plasmodia of the myxomycete Physarum polycephalum. The activity of this enzyme undergoes cyclic fluctuations during the synchronous nuclear cycle with a minimum in early G2-phase and a maximum around the time of mitosis. |
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