|
|||||
|
|
The Effects of Iron-Mediated Oxidative Stress in Isolated Renal Cortical Brush Border Membrane Vesicles at Normothermic and Hypothermic Temperatures |
|
| Authors: | R Horton Catherine Rice-Evans B J Fuller |
| Institution: | a Department of Biochemistry Royal Free Hospital School of Medicine, University, of London, Rowland Hill St, London, UK b Surgery, Royal Free Hospital School of Medicine, University, of London, Rowland Hill St, London, UK |
| Abstract: | Experiments on renal cortical brush border membrane vesicles have been undertaken in order to assess the involvement of iron in oxidative stress at physiological temperatures and under conditions of hypothermia. A decrease in temperature stimulated iron-induced lipid peroxidation. The results are discussed in relation to the role of the oxidation state of the iron and iron(II)/iron(III) ratios in the initiation of peroxidative events. |
| Keywords: | Iron lipid peroxidation renal BBMV hypothermia iron II/iron III ratios |
| 本文献已被 InformaWorld 等数据库收录！ | |