A requirement for three cell types for in vitro generation of specific secondary cell-mediated cytotoxic response against SV40-induced tumor-associated antigens in mice |
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Authors: | M Glaser |
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Affiliation: | Department of Biochemistry, The George Washington University School of Medicine and Health Sciences, Washington, D.C. 20037 USA |
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Abstract: | The present study demonstrates that a collaborative interaction among three cell types, namely, two distinct subsets of T cells and macrophages is needed for in vitro generation of specific secondary cell-mediated cytotoxicity against syngeneic SV40-transformed cells in mice. These data suggest a central role of three cell types in the generation of efficient antitumor immune response in syngeneic tumor systems. |
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Keywords: | To whom reprint requests should be addressed. Immunology Unit Dept. of Bacteriology Univ. of Sydney Sydney 2006 Australia. |
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