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A requirement for three cell types for in vitro generation of specific secondary cell-mediated cytotoxic response against SV40-induced tumor-associated antigens in mice
Authors:M Glaser
Affiliation:Department of Biochemistry, The George Washington University School of Medicine and Health Sciences, Washington, D.C. 20037 USA
Abstract:
The present study demonstrates that a collaborative interaction among three cell types, namely, two distinct subsets of T cells and macrophages is needed for in vitro generation of specific secondary cell-mediated cytotoxicity against syngeneic SV40-transformed cells in mice. These data suggest a central role of three cell types in the generation of efficient antitumor immune response in syngeneic tumor systems.
Keywords:To whom reprint requests should be addressed. Immunology Unit   Dept. of Bacteriology   Univ. of Sydney   Sydney 2006   Australia.
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