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Clostridium carboxidivorans Strain P7T Recombinant Formate Dehydrogenase Catalyzes Reduction of CO2 to Formate
Authors:Apostolos Alissandratos  Hye-Kyung Kim  Hayden Matthews  James E. Hennessy  Amy Philbrook  Christopher J. Easton
Affiliation:CSIRO Biofuels Research Cluster, Research School of Chemistry, Australian National University, Canberra, Australia
Abstract:
Recombinant formate dehydrogenase from the acetogen Clostridium carboxidivorans strain P7T, expressed in Escherichia coli, shows particular activity towards NADH-dependent carbon dioxide reduction to formate due to the relative binding affinities of the substrates and products. The enzyme retains activity over 2 days at 4°C under oxic conditions.
Keywords:
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