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Bim,a Proapoptotic Protein,Up-regulated via Transcription Factor E2F1-dependent Mechanism,Functions as a Prosurvival Molecule in Cancer
Authors:Raghu Gogada  Neelu Yadav  Junwei Liu  Shaohua Tang  Dianmu Zhang  Andrea Schneider  Athul Seshadri  Leimin Sun  C. Marcelo Aldaz  Dean G. Tang  Dhyan Chandra
Affiliation:From the Department of Pharmacology and Therapeutics, Roswell Park Cancer Institute, Buffalo, New York 14263 and ;the §Department of Molecular Carcinogenesis, University of Texas M. D. Anderson Cancer Center, Smithville, Texas 78957
Abstract:
Keywords:Apoptosis   Bcl-2 Family Proteins   Cancer   Cell Signaling   Mitochondria   Bax/Bak   Bcl-xL/Mcl-1   Bim   E2F1   Microtubules
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