Gas chromatographic analysis of oxidation products of adrenal corticosteroids |
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| Affiliation: | 1. Institute of Applied Microbiology, University of Tokyo, Tokyo, Japan;2. the Institute of Physical and Chemical Research, Bunkyo-ku, Tokyo, Japan;1. Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, 3584 CG Utrecht, The Netherlands;2. Research and Development Department, Tiofarma B.V., Hermanus Boerhaavestraat 1, 3261 ME Oud-Beijerland, The Netherlands;3. Department of Clinical Pharmacy, Division of Laboratory Medicine & Pharmacy, University Medical Centre Utrecht, P/O Box 85500, 3508 GA Utrecht, The Netherlands |
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| Abstract: | Gas chromatographic separations of periodic acid and sodium bismuthate oxidation products of corticosteroids, including cortexolone, cortisone, cortisol, prednisolone, deoxycorticosterone, dehydrocorticosterone, and corticosterone, were investigated using SE-30, QF-1, and XE-60 phases. |
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