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Data,Reagents, Assays and Merits of Proteomics for SARS-CoV-2 Research and Testing

Authors:	Jana Zecha Chien-Yun Lee Florian P. Bayer Chen Meng Vincent Grass Johannes Zerweck Karsten Schnatbaum Thomas Michler Andreas Pichlmair Christina Ludwig Bernhard Kuster

Affiliation:	1. Chair of Proteomics and Bioanalytics, Technical University of Munich, Freising, Germany;2. Bavarian Center for Biomolecular Mass Spectrometry (BayBioMS), Technical University of Munich, Freising, Germany;3. Institute of Virology, School of Medicine, Technical University of Munich, Munich, Germany;4. German Center for Infection Research (DZIF), Munich partner site, Germany;5. JPT Peptide Technologies GmbH, Berlin, Germany

Abstract:	Download : Download high-res image (114KB) Download : Download full-size image Highlights •In-depth proteomes of 4 SARS-CoV-2 cell line models (Vero E6, Calu-3, Caco-2, A549). •Proteomic evidence for thousands of Chlorocebus sabaeus proteins. •Proteomic response of Vero E6 cells to SARS-CoV-2 infection. •Synthetic peptides, spectral libraries, and targeted assays for SARS-CoV-2 proteins.

Keywords:	mass spectrometry label-free quantification targeted mass spectrometry parallel reaction monitoring clinical proteomics ACE2 COVID-19 SARS-CoV-2 stable-isotope labeling Vero E6
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