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Proteomic Analysis of Salmonella-modified Membranes Reveals Adaptations to Macrophage Hosts
Institution:3. Division of Microbiology, School of Biology/Chemistry, University of Osnabrück, Osnabrück, Germany;4. CellNanOs – Center for Cellular Nanoanalytics Osnabrück, School of Biology/Chemistry, University of Osnabrück, Osnabrück, Germany;5. Institute of Environmental Change and Society, Department of Biology, University of Regina, Regina, Canada;6. Department of Biology, Faculty of Science, Luther College at University of Regina, Regina, Canada
Abstract:
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  • Highlights
    • •Affinity-based proteomics of infected macrophage cells.
    • Salmonella-modified membranes exhibit host-specific composition.
    • •Proteome differences explain some host-dependent pathophysiological differences.
    Keywords:Affinity proteomics  host-pathogen interaction  pathogens  bacteria  virulence  subcellular analysis  immune cells  intracellular trafficking  Salmonella
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