The influence of medium components on the differentiation period and the life expectancy of the mouse neuroblastoma cells NIE-115 |
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| Authors: | K. B. Aslanidi S. N. Myakisheva |
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| Affiliation: | 1.Institute of Theoretical and Experimental Biophysics,the Russian Academy of Sciences,Pushchino, Moscow oblast,Russia;2.Institute of Cell Biophysics,Russian Academy of Sciences,Pushchino, Moscow oblast,Russia |
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| Abstract: | The rate of differentiation and longevity of mouse neuroblastoma cells NIE-115 in culture media of various compositions have
been investigated. In serum-free media the dependence of the differentiation period on concentrations of sodium ions, amino
acids, and carbohydrates as well as on the pH values had maximum. Differentiated cells exhibited maximal longevity in those
media in which the differentiation time was comparable with the duration of the cellular cycle. |
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