Synthesis and biological evaluation of 9-(beta-L-arabinofuranosyl)adenine |
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| Authors: | Boudou V Imbach J L Gosselin G |
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| Affiliation: | Laboratoire de Chimie Bioorganique, UMR C.N.R.S. 5625, Université de Montpellier II, Sciences et Techniques du Languedoc, France. |
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| Abstract: | ![]()
For the first time, the stereospecific synthesis of 9-(beta-L-arabinofuranosyl) adenine was carried out. Unfortunately, and unlike its "natural" D-counterpart Vidarabine, this L-enantiomer did not show significant activity when evaluated against a broad range of viruses. |
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