Citrullination, a possible functional link between susceptibility genes and rheumatoid arthritis |
| |
Authors: | Vossenaar Erik R Zendman Albert JW Van Venrooij Walther J |
| |
Institution: | Department of Biochemistry, University of Nijmegen, The Netherlands. e.vossenaar@ncmls.kun.nl |
| |
Abstract: | Antibodies directed to citrullinated proteins (anti-cyclic citrullinated peptide) are highly specific for rheumatoid arthritis (RA). Recent data suggest that the antibodies may be involved in the disease process of RA and that several RA-associated genetic factors might be functionally linked to RA via modulation of the production of anti-cyclic citrullinated peptide antibodies or citrullinated antigens. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |