Abstract: | Neurons in the cortex of the segmental ganglia of Haemopis sanguisuga accumulated 3H]DOPA in vitro. Electron microscopic autoradiography revealed deposits of silver grains over clusters of electron dense granules measuring 20-35 nM in diameter. 3H]Dopamine (DA) was localized in the giant glial cells. Dopaminergic terminals were labelled with both DOPA and dopamine and the morphology is similar to other DA synapses. The leech could be a useful model for the study of synaptic events at dopaminergic terminals. |