Bikunin and α1-microglobulin in human zona pellucida and connective tissue |
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| Authors: | Lars Dum Henrik W Nielsen |
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| Institution: | (1) Department of Clinical Biochemistry, Bispebjerg Hospital, University of Copenhagen, Bispebjerg;(2) Department of Pathology, Frederiksberg Hospital, Copenhagen, Denmark |
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| Abstract: | The occurrence of bikunin and ·1-microglobuli n was investigated in human ovary and Fallopian tubes. Bikunin and ·1-microglobulin are transcribed in the liver from a common gene. Bikunin immunoreactivity was detected in the zona pellucida.
A positive reaction for bikunin was also observed in connective tissue of the oviduct. In addition, mast cells showed a more
intense posi tive reaction than the surrounding connective tissue. Specific displaceable ·1-microglobulin immunoreactivity was revealed in the zona pellucida. The data suggest that bikunin and ·1- microglobulin are trapped in the zona pellucida.
This revised version was published online in November 2006 with corrections to the Cover Date. |
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