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A new chromatographic instrument for measuring trace concentrations of breath-hydrogen
Authors:N.Thomas Christman  Lyle H. Hamilton
Abstract:A new instrument has been developed which offers many advantages over instruments presently utilized for the measurement of breath-hydrogen used to evaluate the intestinal absorption of sugars. The gas analyzer has a solid-state sensor which is more specific for hydrogen than most conventional chromatographic detectors. Air can be used as the carrier gas and can be circulated with a small internal pump, thereby eliminating large carrier gas tanks and pressure regulators. The intersample time is approximately 2 min, allowing rapid serial analysis of breath samples. A unique feature allows a short-term memory circuit to recall the signal and present it on a digital panel meter in parts per million. Recorder terminals on the back permit the generation of a permanent record, if desired. The gas analyzer is small, lightweight and simple to operate. Its application to the serial measurement of hydrogen in alveolar air after ingestion of sugars is demonstrated.
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