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Evolution of C4 Phosphoenolpyruvate Carboxylase: Enhanced Feedback Inhibitor Tolerance Is Determined by a Single Residue
摘    要:Dear Editor, Phosphoenolpyruvate carboxylase (PEPC) is the essential enzyme for initial carbon fixation in C4 photosynthesis. The C4-PEPC evolved from a non-photosynthetic C3 ancestor by subtle sequence changes resulting in distinctly different kinetic and regulatory characteristics (Svensson et al., 1997). Malate and aspartate, which are formed from the carboxyla- tion product of PEPC, serve as feedback inhibitors of the PEPC (Wedding et al., 1990). Higher malate or aspartate concen- trations during C4 photosynthesis require a reduced sensitiv- ity towards the feedback inhibitors of the C4-PEPC (Jacobs et al., 2008).

关 键 词:磷酸烯醇式丙酮酸羧化酶  抑制剂  残留测定  反馈  耐受性  Svensson  演变  PEPC
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