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Rexinoid inhibits Nrf2-mediated transcription through retinoid X receptor alpha |
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| Authors: | Jiaguo Wu Hongyan Wang Xiuwen Tang |
| Affiliation: | 1. Division of Gastroenterology, Sir Run Run Shaw Hospital, Zhejiang University, Hangzhou 310058, PR China;2. Department of Biochemistry and Genetics, School of Medicine, Zhejiang University, Hangzhou 310058, PR China |
| Abstract: | |
| Keywords: | AKR1C, aldo-keto reductase 1C ATRA, all-trans retinoic acid ARE, antioxidant response element CTCL, cutaneous T-cell lymphoma DMSO, dimethyl sulfoxide GFP, green fluorescent protein GST, glutathione S-transferase HO-1, heme oxygenase 1 KEAP1, Kelch-like ECH-associated protein 1 NQO1, NAD(P)H:quinone oxidoreductase 1 Nrf2, NF-E2 p45-related factor 2 RT-PCR, real-time quantitative PCR NSCLC, non-small-cell lung cancer RAR, retinoic acid receptor RXRα, retinoid X receptor alpha siRNA, small interfering RNA tBHQ, tert-butylhydroquinone |
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