GeneCards 2002: towards a complete,object-oriented,human gene compendium |
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| Authors: | Safran Marilyn Solomon Irina Shmueli Orit Lapidot Michal Shen-Orr Shai Adato Avital Ben-Dor Uri Esterman Nir Rosen Naomi Peter Inga Olender Tsviya Chalifa-Caspi Vered Lancet Doron |
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| Affiliation: | Departments of Molecular Genetics Biological Services (Bioinformatics Unit) Molecular Cell Biology, The Weizmann Institute of Science, Rehovot, Israel. marilyn.safran@weizmann.ac.il |
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| Abstract: | MOTIVATION: In the post-genomic era, functional analysis of genes requires a sophisticated interdisciplinary arsenal. Comprehensive resources are challenged to provide consistently improving, state-of-the-art tools. RESULTS: GeneCards (Rebhan et al., 1998) has made innovative strides: (a). regular updates and enhancements incorporating new genes enriched with sequences, genomic locations, cDNA assemblies, orthologies, medical information, 3D protein structures, gene expression, and focused SNP summaries; (b). restructured software using object-oriented Perl, migration to schema-driven XML, and (c). pilot studies, introducing methods to produce cards for novel and predicted genes. |
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