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Abietane diterpenoids and other constituents from Clerodendrum trichotomum
Institution:1. Department of Pharmaceutical Engineering, School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, PR China;2. State Key Laboratory Cultivation Base for the Chemistry and Molecular Engineering of Medicinal Resources, Guangxi Normal University, Guilin 541004, PR China;3. Jiangsu Province Hi-Tech Key Laboratory for Bio-medical Research, Southeast University, Nanjing 211189, PR China
Abstract:The genus Clerodendrum Linn., originally belonging to Verbenaceae, was assigned to Lamiaceae by APG (Angiosperm Phylogeny Group) Ⅱ. Seven abietane diterpenoids (1–7) along with three anthraquinones (810) and one neolignan (11) were isolated and identified from the stems of Clerodendrum trichotomum Thunb.. Among them, compounds 4, 6 and 811 were reported from the genus Clerodendrum Linn. for the first time. Compounds 1, 3 and 7 were obtained from this species for the first time. Isolation of abietane diterpenoids from C. trichotomum could further comfirm that the genus Clerodendrum belongs to Lamiaceae rather than Verbenaceae.
Keywords:Abietane diterpenoids  Lamiaceae  Chemotaxonomy
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