Pyrrolo[2,1-c][1,4]benzodiazepine-anthraquinone conjugates. Synthesis, DNA binding and cytotoxicity |
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Authors: | Kamal Ahmed Ramu R Khanna G B Ramesh Saxena Ajit Kumar Shanmugavel M Pandita Renu Moti |
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Affiliation: | Division of Organic Chemistry-I, Indian Institute of Chemical Technology, Hyderabad 500 007, India. ahmedkamal@iict.res.in |
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Abstract: | New pyrrolobenzodiazepine-anthraquinone hybrids have been designed and synthesized, found to effectively bind to DNA and also exhibit cytotoxicity against many cancer cell lines |
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