Intraspinal Tumors in Children |
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Authors: | James E Boggan Julian T Hoff Edwin B Boldrey William M Wara |
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Institution: | Department of Neurological Surgery, University of California, San Francisco;Department of Radiation Oncology, University of California, San Francisco |
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Abstract: | Thirty cases of intraspinal neoplasms occurring during the first two decades of life are reviewed. Histologic examination showed 13 of these to be astrocytomas, 6 neuroblastomas, 5 sarcomas, 3 ependymomas, 2 neurofibromas and 1 a schwannoma. Orthopedic deformities developed or worsened in 60 percent of patients surviving longer than a year after diagnosis. In five patients some form of endocrine deficiency developed after irradiation. For treatment of radiosensitive extradural malignant lesions, biopsy followed by irradiation is advocated. |
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