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Meeting report: the terabase metagenomics workshop and the vision of an Earth microbiome project
Authors:Gilbert Jack A  Meyer Folker  Antonopoulos Dion  Balaji Pavan  Brown C Titus  Brown Christopher T  Desai Narayan  Eisen Jonathan A  Evers Dirk  Field Dawn  Feng Wu  Huson Daniel  Jansson Janet  Knight Rob  Knight James  Kolker Eugene  Konstantindis Kostas  Kostka Joel  Kyrpides Nikos  Mackelprang Rachel  McHardy Alice  Quince Christopher  Raes Jeroen  Sczyrba Alexander  Shade Ashley  Stevens Rick
Abstract:Between July 18(th) and 24(th) 2010, 26 leading microbial ecology, computation, bioinformatics and statistics researchers came together in Snowbird, Utah (USA) to discuss the challenge of how to best characterize the microbial world using next-generation sequencing technologies. The meeting was entitled "Terabase Metagenomics" and was sponsored by the Institute for Computing in Science (ICiS) summer 2010 workshop program. The aim of the workshop was to explore the fundamental questions relating to microbial ecology that could be addressed using advances in sequencing potential. Technological advances in next-generation sequencing platforms such as the Illumina HiSeq 2000 can generate in excess of 250 billion base pairs of genetic information in 8 days. Thus, the generation of a trillion base pairs of genetic information is becoming a routine matter. The main outcome from this meeting was the birth of a concept and practical approach to exploring microbial life on earth, the Earth Microbiome Project (EMP). Here we briefly describe the highlights of this meeting and provide an overview of the EMP concept and how it can be applied to exploration of the microbiome of each ecosystem on this planet.
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