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Kinetic Advantage of Intrinsically Disordered Proteins in Coupled Folding-Binding Process: A Critical Assessment of the “Fly-Casting” Mechanism |
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| Authors: | Yongqi Huang |
| Institution: | College of Chemistry and Molecular Engineering, Center for Theoretical Biology, State Key Laboratory for Structural Chemistry of Unstable and Stable Species, Peking University, Beijing 100871, China Beijing National Laboratory for Molecular Sciences, Peking University, Beijing 100871, China |
| Abstract: | |
| Keywords: | IDP intrinsically disordered protein KID kinase-inducible domain pKID phosphorylated KID KIX kinase-inducible domain interacting domain MFPT mean first passage time MPT mean passage time SA spectrophotometric assay SPR surface plasmon resonance SF stopped flow RMB resonant mirror biosensor QCM quartz crystal microbalance |
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