Effects of Codonopis bulleynana forest ex diels on Deferribacteres in constipation predominant intestine tumor: Differential analysis |
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| Authors: | Yanmei Li Yunpeng Luan Xiaoguang Yue Fei Xiang Dechang Mao Yong Cao Zhi Xiong |
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| Institution: | 1. Key Laboratory for Forest Resources Conservation and Utilization in the Southwest Mountains of China, Ministry of Education, Southwest Forestry University, China;2. Department of Life Technology Teaching and Research, School of Life Science, Southwest Forestry University, China;3. Wenzhou Business College, Wenzhou, China;4. Department of Life Technology Teaching and Research, College of Life Sciences, Southwest Forestry University, China;5. Yuxi Genor Biotechnology Co., Ltd, China;6. Light Industry and Food Engineering College, SWFU, Bailongsi, China |
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| Abstract: | As a complicated micro-ecosystem, gut microbes are closely related to metabolic disease, immune disease and tumor (such as constipation. Long-term constipation would cause intestinal mucosal injury, enteritis, ileus, etc., thus inducing intestine cancer). In this research, intestine cancer model group and Codonopsis foetens treatment group were successfully constructed, and the variation of intestinal microbes were analyzed by 16S rRNA sequence. Results showed that there were changes in bacteria abundance of Firmicutes, Bacteroidetes, Proteobacteria, Deferribacteres, Tenericutes, and Actinobacteria, etc. Codonopsis foetens could directly or indirectly affect the growth and metabolism of Deferribacteres by altering the nutritional ingredient and pH value of intestine “medium”, thus affecting the occurrence and development of intestinal microbes. |
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| Keywords: | Codonopsis foetens Deferribacteres Intestine tumor 16S rRNA sequence |
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